A quick response against Periimplantitis can prevent implant loss

Patented solution of Hyaluronic acid with active protection

Scientific studies have proven that the prevalence of the disease in it’s different variations can range from 10 to 60%, affecting all types of implants and connections. Periimplantitis will become one of the most usual dental problems the way to treat it a differentiation point for dental practices.

Application of Implaprotect combats biofilm affecting soft tissue (and eventually bone). Hyaluronic acid acts as barrier for pathogens and stimulant for living tissues, enabling recovery, fostering growth, and creating sustainable healthy and aesthetic result within days. It’s use is also recommended when placing an implant as it increases bone and implant surface protection with it’s physical barrier towards pathogens




Implaline’s exclusive formula with high density Hyaluronic acid, creates a barrier over the affected area, covering the wound to facilitate the healing. However, to avoid bacterial attack to the protective layer, the HA is combined with an locally active adjuvant to ensure that its physical activity is preserved during the length of the treatment.

Surgical stage approach usually done in less than 45 minutes that includes:

Local decontamination (with our exclusive patented formula)
Long term protection and regeneration aid (high density hyaluronic acid plus bone substitute)

Positive long term outcome (12 months+) that includes:

Reduced suppuration on probing from 49% to 0% 
Reduced BOP measurement from 100% to 14%
Average bone gain 3,22 mm


Use Implacure to

Treat peri-implantitis without implant extraction, increasing treatment options as well as improving clinical performance

A Patented Treatment Protocol with Results

With several cases treated during the product-development phase, ongoing trials show:

  • Excellent long-term results: strong defect reduction, with very good aesthetic results

  • Strong short and medium-term results: excellent results after 8 days in 84% of patients and `good’ in 16%

Product benefits

  • Increased chances of saving existing implant
  • Patients and professionals can see visible improvements within the first 24 hours
  • Less discomfort for patients
  • Hyaluronic acid supports bone regeneration
  • Implacure offers proven long term success of treated implants, allowing for regular maintenance and, if needed, retreatment
  • Minimizes the risk of lack of patient compliance

Use Implaprotect

  • Treat peri-implant mucositis (no bone loss)

  • Increase safety during implant placement

  • Protect tissue regeneration of future implant placement site


A Patented Local Action with Rapid Results

  • Acts as a barrier between body tissues and germs

  • Improves osteogenic and osteoinductive activity

Product benefits:

  • Area protection: significantly reducing the risk of infection while enhancing tissue regeneration

  • Delays/prevents bone loss in patients suffering from peri-implant mucositis
  • Non-surgical recurring treatment that can be carried out during regular visits
  • When applied to a new implant, 100% of treated cases are well osseointegrated after 3 to 4 months

  • Faster bone regeneration in post-extraction sites when compared to other treatments 

  • Better implant insertion because of Implaprotect’s patented use of hyaluronic acid

  • Rapid re-ossification of extraction sites


Why Piperacillin Tazobactam to protect the physical action of the film?


Piperacillin Tazobactam has proven to be effective against almost all families of bacteria. Given the huge variance of bacteria present in the mouth and the periodontal pockets, a broad spectrum solution to prevent infection or destruction of the physical action of the product is needed.

Piperacillin-Tazobactam, applied only in the right proportion, is an integral part of the physical activity, ensuring the protection of the high density Hyaluronic Acid during the length of the treatment.


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2) Brunel G et al. Action of hyaluronic acid on the wound healing following extraction. Dent inform 2004; 7: 385–91.
3) Sasaki T, Watanabe C. Stimulation of osteoinduction in bone wound healing by high-molecular hyaluronic acid, Bone 1995; 16(1): 9–15.
4) Azlan M et al. The effect of hyaluronic acid-supplemented bone graft in bone healing: experimental study in rabbits, Bio App 2006; 20(3): 209–20.
5) Sasaki T, Watanabe C. Stimulation of osteoinduction in bone wound healing by high-molecular hyaluronic acid, Bone 1995; 16(1): 9–15.
6) Azlan M et al. The effect of hyaluronic acid-supplemented bone graft in bone healing: experimental study in rabbits, Bio App 2006; 20(3): 209–20.
7) Bartoloni S, Omer G. Peri-implant infections: prevention and treatment with a gel containing sodium hyaluronate and piperacillin and tazobactam, Doctor Os; 2014.
8) Conference, Santos Marino J. Treatment of Periimplant deseases. SEI Madrid, Spain. 2019
9) Zheng H, et al. Subgingival microbiome in patients with healthy and ailing dental implants. Sci Rep. 2015;16;5:10948. Ata J Candel ME, Flichy AJ, Penarrocha D, Balaguer JF, Penarrocha DM. Periimplantitis: associated microbiota and treatment. Med Oral Patol Oral Cir Bucal 2011;16(7):e937-e943
10) Wellington ICU Drug Manual, Antibiotic sensitivity overview. Appendix 5
11) Romanò CL, et al. Hyaluronic Acid and Its Composites as a Local Antimicrobial/ Antiadhesive Barrier. J Bone Jt Infect 2017; 2(1):63-72

Manufactured by:

Lettenweg 132
CH-4123 Allschwil
+41 (0)61 225 60 68 / 69


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